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50 Cent first criticized Madonna's looks in December 2021.

50 Cent is “Hung Up” on criticizing Madonna. The “Candy Shop” rapper, 48, slammed the 65-year-old “Material Girl” on Instagram Friday by comparing her butt to an animated ant’s. “Who the fvck did this?” 50, whose legal name is Curtis James Jackson III, captioned the post in which he placed a recent video of Madonna performing at London’s O2 Arena next to a clip art ant, seemingly comparing the two’s derrieres. “She’s rich how the hell she didn’t get it fixed I want the fvcking doctors name right now,” he continued on Madge’s alleged plastic surgery . “I mean damn it man ! LOL #bransoncognac #lecheminduroi.” The Post has contacted reps for 50 Cent and Madonna for comment. In November, 50 referred to Madonna as his “grandma” after she shared several seductive social media posts . Her former friend previously compared one of her risqué photos to aliens last June in a since-deleted Instagram post. “I hope she didn’t make her kids take this picture. LOL at 63 somebody tell her to chill out please,” 50 captioned the photos at the time. A post shared by 50 Cent (@50cent) “Here is 50 Cent pretending to be my friend,” she captioned an Instagram Story selfie of them. “Now you have decided to talk smack about me. I guess your new career is getting attention by trying to humiliate others on social media. The least elevated choice you could make as an artist and an adult.” The “Vogue” songstress previously clapped back at the “P.I.M.P” rapper when he first criticized her lingerie photos in December 2021. “Here is 50 Cent pretending to be my friend,” she captioned an old photo of the post on her Instagram Story at the time. “Now you have decided to talk smack about me. I guess your new career is getting attention by trying to humiliate others on social media. The least elevated choice you could make as an artist and an adult.” She added, “You’r just jealous you won’t look as good as me or have as much fun when you are my age.” Madonna recently revealed that she didn’t think she would survive a bacterial infection that caused her to postpone her “Celebration Tour” over the summer. Read more